While marred by some blurry images and slightly awkward graphic design, the content of this book is fantastic. Diseases are an anemic part of the fifth edition ruleset, and it's easy to see why: they're unsatisfying to fight in a game of heroic fantasy! This book deftly leaps over this hurdle by couching its new rules in the context of a wizard hellbent on slaying adventurers by the thousands with epidemic contagions.
This book gets slightly more technical than I'd like in my fantasy by using modern medical terms rather than medieval medical jargon. While this shows off the authors' scientific pedigree, I would be hard pressed to find anyone in a D&D world with knowledge this precise. Nevertheless, this book is brimming with techniques to create realistic and complex diseases, complete with methods of transmission and cures.
The Malady Workshop is a useful tool for any Dungeon Master interested in creating inventive and perfidious diseases. I only wish its presentation were a bit tighter, but that won't stop me from giving it five stars. Great work!