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The Malady Codex: The Guide to DiseasesClick to magnify
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The Malady Codex: The Guide to Diseases


You can now explore even deadlier maladies in the Seven Deadly Plagues!


This supplement is written by medical students with a love for tabletop roleplaying games. Inspired by the vast array of diseases, and the medieval myths that once surrounded them, we embarked on a mission; to enrich other worlds with fantastical diseases.

Deep in each civilization’s roots, there are myths, remedies, and folklore, all revolving around the ailments that affect its people. When each Dungeon Master wants to expand on the details of the societies that unfold before their very eyes, tools that spice up the process become a vital weapon. This supplement will hopefully become one of them, as DMs become inspired by the grim, epic or mundane conditions of the human body and mind.

Do not underestimate diseases. Part of the Dungeon Master’s art is to be able to stir feelings up in their players, and few human conditions could accomplish that better. Used as a way to advance a storyline, to expand a character arc or to create conflict, the following stories can serve you well!

In this book, you'll find 11 fully detailed diseases, including:

  • The Druid's Curse, The Mad Mage's Virus, the Mindflayer Network, Talona's Curse and the infamous ISTD.
  • Details on the origins, symptoms, and cures for all these maladies.
  • Tips on how to implement each one in your games, making your life just a bit easier.
  • New NPCs, monsters and items to challenge and reward your players with.
  • A useful table to consult when deciding what specific spells affect what disease.
  • A visual representation chart of the progression of the Mad Mage's Virus.

"This makes want to roll up a character whose reason for adventuring is to find out everything there is to know about these diseases." - Marcus Santos, editor.

"If you are looking for a believable way to integrate diseases into your campaign, you cannot do better than the Malady Codex." - DM Dango, reviewer

"... this codex is an interesting, useful, and fun way to add a bit of grit into your campaign." - DMLevelUp, reviewer

"Disease and pestilence are as much a part of D&D as anything else, yet few would dare create an entire supplemental guide exploring new and virulent maladies." - Eric Watson, reviewer

"If you use this supplement sparingly and effectively your players will talk about it for years to come." NZS Games, reviewer

Give your worlds a touch of fantastical realism and watch as your players dive deep into the stories you create with these tools!

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Reviews (13)
Discussions (5)
Customer avatar
Robert M June 01, 2020 8:21 pm UTC
One thing I'm a little unclear on with the Mad Mage disease is what spawns what version of the Virus. It seems like if the host dies in Stage 1, you get the Gp41. If they die during Stage 2 it's the Gp120 that spawns. But the text in the Virus, progression chart, and the Monster section do not specify which version would spawn if the disease gets to Stage 3. Considering the Monster section has Gp120 leading Gp41, I'm imagining it would be the Gp120 that spawns at Stage 3 when the host gets cured automatically? However the Monster section implies it's the Gp41 that always spawns, and the Gp120 occurs naturally?
Customer avatar
Tommy H March 26, 2020 11:18 am UTC
The "DiseaseTable.png" is not included like it says it should be in the Appendix D: Diseases section. Would love it if i could get my hands on it :)
Customer avatar
Simon F February 27, 2019 12:29 am UTC
Page 5, "Cure" para 2, "lighting-like" should be "lightning-like"
Page 5, "Cure" para 3, "protected by spells" should be "protected from spells"
Customer avatar
January 02, 2019 3:32 am UTC
Is there a particular reason the two tables weren't included in the pdf as well as in individual image form?
Customer avatar
Jens S December 30, 2018 5:17 pm UTC
The resolution of the 1408145-ProgressionTable is WAY to low, cannot be read. Otherwise, great product.
Customer avatar
Themistoklis P December 30, 2018 8:11 pm UTC
Thank you for commenting, we will update as soon as possible. Excuse us for any inconvenience.
Customer avatar
Jason B December 31, 2018 6:01 pm UTC
Thank you for pointing this out. The table has been replaced with one with a better resolution.
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File Last Updated:
December 31, 2018
This title was added to our catalog on October 27, 2018.